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Feb 23, 2023
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A pharmaceutical rubber stopper is a rubber elastomer product with a certain shape and size, used for sealing the mouth of the glass, plastic, and other medical bottle containers. Its structure can be roughly divided into three categories: tapered, T-shaped, and flanged; According to the use, it can be divided into antibiotic stoppers, biological pharmaceutical stoppers, spray corks, and infusion stoppers. The stopper compound is required to be free of harmful soluble substances such as lead, mercury, arsenic, barium, etc., which do not work with the loadable agent, and the stopper itself cannot have ejections. Widely used in the pharmaceutical and medical industries.
Types of Rubber Stoppers for Pharmaceuticals PDF
Antibiotics & Injection Rubber Stopper
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Proactive Technical Support of Pharmaceutical Rubber Stopper
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Features of Pharmaceutical Rubber Stopper
The rubber stopper for pharmaceutical use is an integral part of medicine. Its main function is to seal and store the medicine in a relatively small aseptic inert environment, isolated from the external common environment so that the medicine can maintain its efficacy within the validity period. If there is an abnormality in the rubber stopper, the medicine may become invalid or even deteriorate, posing a threat to the lives of the people. The physical properties of the rubber stopper play a decisive role in the sealing of the medicine. The physical properties of rubber stoppers are very important and indispensable to the quality of medicines.
FAQs of Pharmaceutical Rubber Stopper
QWhat is the use of rubber stopper for injection in laboratory?
Rubber stoppers are ideal for plugging joints or holes in laboratory glassware and creating a liquid-tight seal. Rubber bungs are often used with glass containers such as test tubes, flasks, jugs, and many other pieces of standard lab equipment.
QWhat is rubber closure?
Rubber Closures (Stoppers) provide a barrier between the neck of a vial and the vial contents and thus maintaining sterility and preventing contamination. It creates an air- and fluid-proof seals in containers. Rubber Stoppers are available in Synthetic and Natural Polymers.
QWhat are Pharmaceutic closures?
Pharmaceutical closures, also known as stoppers or bungs, are an important part of the final packaging of pharmaceutical preparations, particularly those that are intended to be sterile. The most commonly used type of stopper is the elastomeric closure.
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Medical rubber stoppers are commonly used in the pharmaceutical industry for sealing vials, bottles, and other containers that hold medication. Here are some key points about the rubber stopper for pharmaceutical use:
Containment and Sealing: Rubber stoppers for pharmaceuticals serve as an effective barrier, ensuring the containment and integrity of the medication within the container. They provide an airtight and leak-proof seal, preventing the entry of contaminants, moisture, and oxygen, which can degrade the medication or compromise its sterility.
Compatibility: Medical rubber stoppers including butyl rubber stopper for injection vials are selected based on their compatibility with the specific medication and its formulation. Different types of rubber, such as bromobutyl or chlorobutyl, are chosen to ensure compatibility with the drug and its potential interaction with the closure system.
Sterility: Medical rubber stoppers are manufactured and treated under controlled conditions to maintain their sterility. They are typically sterilized before use, either through steam sterilization or other validated methods, to ensure that they do not introduce microbial contaminants into the medication.
Closure Integrity: Rubber stoppers for pharmaceuticals are designed to provide a secure closure that resists accidental removal or tampering. This feature ensures the safety and quality of the medication and helps maintain the product's shelf life.
Parenteral Applications: Pharmaceutical stoppers are particularly crucial in parenteral applications, such as injectables and infusions, where the medication is directly administered into the body. The stoppers must meet strict standards to maintain the sterility and stability of the drug during administration.
Quality Assurance: Rubber stoppers are subject to stringent quality control measures, including testing for factors like extractables, leachables, and particulate matter. These tests ensure that the stoppers do not release harmful substances or contaminants that could compromise the safety and efficacy of the medication.
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